β-Estradiol,β-雌二醇,17β-diol, 17β-Estradiol, Dihydrofolliculin
β-Estradiol β-雌二醇
Sigma E2257 β-Estradiol
powder, BioXtra, γ-irradiated, suitable for cell culture
Synonym: 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin
CAS Number: 50-28-2
Empirical Formula (Hill Notation): C18H24O2
Molecular Weight: 272.38
Beilstein Registry Number: 1914275
EC Number: 200-023-8
MDL number: MFCD00003693
PubChem Substance ID: 24894462
Description:
Application β-Estradiol is used to study cell differentiation and transformations (tumorigenicity).
Reconstitution To prepare 20 μg/ml stock solution: add 1 ml absolute ethanol; gently swirl to dissolve; add 49 ml sterile medium while mixing.
Physical form powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw
Biochem/physiol Actions The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
APPEARANCE: WHITE TO OFF-WHITE POWDER
SOLUBILITY :CLEAR COLORLESS SOLUTION AT 1 MG/ML OF ETHANOL
PURITY BY HPLC: > OR = 98%
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β-Estradiol(17β-Estradiol,β-雌二醇 )
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Sigma
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E2257
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1MG
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1420
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