產(chǎn)品名稱：anti-human PD-1 (CD279) FITC MIH4 100 tests 產(chǎn)品貨號(hào)：eBioscience 11-9969-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD279 (PD-1) FITC Also known as: PD1 Clone: MIH4 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 11-9969 11-9969-41 25 tests 11-9969-42 100 tests Description: The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55 kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.
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