產(chǎn)品名稱：anti-mouse CD9 Purified eBioKMC8 (KMC8) 500 ug 產(chǎn)品貨號(hào)：eBioscience 14-0091-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD9 Purified Also known as: MIC3, Tspan29 Clone: eBioKMC8 (KMC8) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-0091 Cat. No. Size 14-0091-81 50 ug 14-0091-82 100 ug 14-0091-85 500 ug Description: The eBioKMC8 monoclonal antibody reacts with mouse CD9, a 24 kDa member of the transmembrane 4 superfamily. This family is characterized by the presence of four hydrophobic domains spanning the cell membrane and short N- and C-terminal cytoplasmic domains. CD9 is expressed by several cell types including monocytes, macrophages, platelets, early B cells, activated B and T cells, dendritic cells, eosinophils, basophils, endothelial cells, myoblasts and neuroblasts. On T cells, CD9 functions as a co-stimulatory molecule on naïve T cells. Furthermore, CD9 is expressed in oocytes, and CD9-deficiency results in sterility caused by defective gamete fusion. In mouse macrophages, CD9 functionally associates with FcγRs to modify signals for phagocytosis and inflammatory responses. In mouse B cells, it was discovered that CD9 is a marker for marginal zone B cells, B1 cells, and plasma cells. In dendritic cells, recently it was demonstrated that CD9 facilitates the association of heterologous MHC II molecules. The level of CD9 expression is subject to donor variability.
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