產(chǎn)品名稱：Purified Mouse Nestin (clone rat401), 100 ug 產(chǎn)品貨號：eBioscience 14-5843-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse/Rat Nestin Purified Also known as: NES, type VI intermediate filament (IF) protein Clone: Rat-401 (Rat401 (4D4)) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5843 Cat. No. Size 14-5843-80 25 ug 14-5843-82 100 ug Description: The monoclonal antibody Rat-401 recognizes mouse and rat nestin, a Class VI intermediate filament protein (>170 kDa) primarily expressed in neuroepithelial stem cells. Upon neural differentiation, expression is down-regulated and within the ***** nervous system is limited to progenitor cells in the cortical subventricular zone, the hippocampal dentate gyrus, dorsal root ganglia satellite cells, and a subpopulation of Schwann cells. Nestin expression is also present in other progenitor cell populations such as pancreatic islet, angiogenic endothelial cells, and bone marrow mesenchymal stem cells. Nestin filaments require vimentin and desmin for assembly into heterodimers and polymers. Upon differentiation, Nestin-containing filaments are replaced by cell type specific intermediate filament proteins, such as GFAP.
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