產品名稱：Anti-AIM2  Purified (pAb) 100 ul
產品貨號：eBioscience 14-6008-93
產品規格：500 ug
Anti-AIM2 Purified
Also known as: Antigen isolated from Immunoselected Melanoma 2, AIM-2
Clone: Polyclonal
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-6008
Cat. No. Size
14-6008-93  100 uL 
Description: This polyclonal antibody reacts with human, mouse, and rat AIM2 (also known as Antigen isolated from Immunoselected Melanoma 2). A member of the HIN-2000 family, this 40-kDa cytoplasmic protein is expressed in the spleen, small intestine, peripheral blood lymphocytes, and testis. Moreover, AIM2 is expressed in tumors of the neuroectodermis, breast, ovary, and colon. As a component of the inflammosome, AIM2 detects double-stranded viral and bacterial DNA present in the cytosol and initiates Caspase1 activation. Expression of AIM2 can be induced by interferons.

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