產品名稱：Affinity Purified Recombinant human CD40 Ligand 25 ug
產品貨號：eBioscience 14-8502-80
產品規格：25 ug
Human CD154 (CD40 Ligand) Recombinant Protein
Also known as: CD40L, Tnfsf5, TRAP
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-8502
Cat. No. Size
14-8502-62  5 ug 
14-8502-80  25 ug 
Description: CD40 ligand, (CD40L, also known as CD154, TRAP or gp39) is a membrane glycoprotein expressed on activated CD4+ T-cells, NK cells, mast cells, basophils and eosinophils. The CD40-CD40L interaction stimulates B cell immune response which includes cell surface antigen expression, cell cycle activation, Ig isotype switching, Ig secretion and memory generation. The CD40-CD40L interaction also plays important roles in monocyte and dendritic cell activation, T-cell co-stimulation and cytokine production. It has been reported that the CD40-CD40L interaction is involved in the pathogenesis of amyloid pathology in Alzheimer disease.
Recombinant Human CD40L produced in E.Coli is a non-glycosylated, polypeptide containing 149 amino acids and having a molecular mass of 16 kDa.

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