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產品名稱:Anti-Mouse/Human Gata-3 (Gata3) Alexa Fluor® 647 (TWAJ) 100 tests
產品貨號:eBioscience 51-9969-42
產品規格:100 tests
Anti-Human CD279 (PD-1) Alexa Fluor® 647 (Discontinued. Refer to Cat. No. 17-9969)
Also known as: PD1
Clone: MIH4
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: Alternative format APC, Cat. No. 17-9969
SKU# 51-9969
Description: The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55 kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.