產品名稱：Testosterone, free RIA
產    地：Demeditec
產品貨號：DE4369
產品規格：96 Tests
產品說明：
Special remarks:
For IN VITRO determination of Free Testosterone (FT) levels in hirsutism and hypogonadism. Free testosterone diffuses through cell membranes and binds to specific receptor proteins (androgen receptors); the Testosterone-receptor complexes act as transcriptional modulators on cis-regulatory regions of many genes. Excess of Androgens in women causes hirsutism and signs of virilization; Testosterone level in serum has to be determined before and after ovarian and adrenal stimulation and supression to identify the source of excessive hormone production. Primary and secondary hypogonadism in men result in clinical hypoandrogenization, correlated with the degree of gonadal failure in Testosterone production.  The determination of serum Testosterone together with that of LH allows the correct assessement of those conditions. The diagnosis of true anorchia also requires to discriminate this condition from cryptorchidism.  Under prolonged hCG stimulation, Testosterone levels remain very low in true anorchia while cryptorchid testes can respond to stimulation. Androgen resistance syndromes, due to X linked androgen receptor gene deficiencies, are made of various degrees of sexual ambiguity.  Whatever the severity of the phenotypical abnormalities, serum Testosterone is systematically high in regards to elevated LH serum levels in these conditions. Testosterone assays include total testosterone (direct, extraction, coated tubes) and free testosterone determinations. Total Testosterone in plasma includes free Testosterone and Testosterone bound to SHBG, albumin, CBG. The mean percentage of each in normal men is 2.7, 32, 65 and <0.1 respectively. Solvents break the protein binding in extraction assays whereas blocking agents release Testosterone from proteins in direct assays. The advantage of a free testosterone assay is that free testosterone concentrations are in equilibrium with testosterone bound to receptors in the organs.
There is an alternative method available for the measurement of free Testosterone in saliva. This non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering such a testkit in ELISA format with the catalogue number DES6622.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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