產品名稱:CYFRA 21-1 ELISA 產 地:Demeditec 產品貨號:DE5070 產品規(guī)格:96 Tests 產品說明: Special remarks: PRINCIPLE OF THE TEST The DEMEDITEC CYFRA 21-1 ELISA Kit is a solid phase enzyme-linked immunosorbent assay (ELISA) based on the sandwich principle. The microtiter wells are coated with a monoclonal [mouse] antibody directed towards a unique antigenic site of the CYFRA21-1 molecule. An aliquot of patient sample containing endogenous CYFRA21-1 is incubated in the coated well with enzyme conjugate, which is an anti- CYFRA21-1 monoclonal antibody conjugated with horseradish peroxidase. After incubation the unbound conjugate is washed off. The amount of bound peroxidase is proportional to the concentration of CYFRA21-1 in the sample. Having added the substrate solution, the intensity of colour developed is proportional to the concentration of CYFRA21-1 in the patient sample. Summary and Explanation CYFRA 21-1 is a fragment of cytokeratin 19. Although expressed in all body tissues its major occurrence is in the lung, particulary in lung cancer tissues. The major diagnostic importance of CYFRA 21-1 as a tumor marker is in differential diagnosis, prognosis, and aftercare of non-small-cell lung cancer (NSCLC) patients. Additionally, CYFRA 21-1 has been described as a tumor marker for the monitoring of bladder cancer. The CYFRA 21-1 ELISA uses the two mouse monoclonal antibodies KS19.1 and BM19.21 to determine cytokeratin 19 fragments. 上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位,公司提供的產品涵蓋了二十多個國家近五十萬種產品,而且產品的數(shù)量與信息在不斷的增長和更新,公司提供的產品能夠使生命科學工作者加快對生物化學,分子生物學,細胞生物學以及蛋白質組學研究的認知,以及分子診斷和臨床醫(yī)學領域的應用。
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