產品名稱：Poliomyelitis virus IgG ELISA
產    地：Demeditec 
產品貨號：DEPOL01
產品規格：96 Tests
產品說明：
Special remarks: The DEMEDITEC Polio IgG Antibody ELISA Test Kit has been designed for the the detection and the quantitative determination of specific IgG antibodies against Polio in serum and plasma. The antigen used for coating of the microtiter plate is Type 1+2+3, Mahony and Sabin.
Poliomyelitis is an infection caused by enterovirus, which occurs epidemically world-wide, and which often leads to paralysis and death. Three types of human-pathogenic poliomyelitis viruses are actually known:
Type 1 (Brunhilde): often with severe symptoms
Type 2 (Lansing): with milder symptoms
Type 3 (Leon): rare, but with severe symptoms
Polioviruses mainly proliferate in the lymph nodes of the intestine, and are excreted via feces. The throat can also be infected, and the viruses then leave the body orally. After the infection, the viruses are distributed via monocytes into other lymph nodes, where they multiplicate. In a second viremic phase they settle in the whole organism, amongst others in the central nervous system. In more than 90% of the infections the patient does not suffer any subjective symptoms. In the remaining other cases there appear: unspecific illness with slight fever, head and throat irritations, diarrhoea, nausea, and vomiting. Very rarely the classical paralysis with affliction of muscles and cerebral nerves is seen. The reconvalescent phase can last up to two years, frequently there stay long-lasting damages. There exists no treatment of the disease, only symptomatic therapy with acetylsalicylic acid and gymnastics is possible. In many countries of the Asiatic area poliomyelitis is still endemic, but WHO has started ambitious projects to eradicate the disease. In Europe there exist cases which are imported by tourists, sometimes with lethal outcome. The diagnosis of poliomyelitis is performed by direct detection of the infectious agent in stool or throat washings during the incubation time of the virus, or by determination of antibodies in the blood. The latter is usually done by the neutralisation test, where titer differences of paired sera against the three virus types are measured separately. Only recently a Poliomyelitis IgG ELISA assay was developed in analogy to Diphtheria and Tetanus, which can detect antibodies against the three types of Polio simultaneously. This serological response can be due to a past illness or to immunity by vaccination.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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