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Galectin-3 human ELISA

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產(chǎn)品名稱: Galectin-3 human ELISA
產(chǎn)品型號: JP27755
產(chǎn)品展商: 原裝進口
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

Galectin-3 human ELISA


Galectin-3 human ELISA  的詳細介紹
Galectin-3 human ELISA

產(chǎn)品名稱:Galectin-3 human ELISA
產(chǎn)    地:Demeditec 
產(chǎn)品貨號:JP27755
產(chǎn)品規(guī)格:96 Tests
產(chǎn)品說明:
Special remarks:
Cross reactivities have been determined such as
Human Galectin-1         < 0.1%
Human Galectin-4           0.21%
Mouse Galactin-3        < 0.1%
Galectin is widely distributed in nematodes, insects, and porifers, as well as vertebrates, and it has also been found to be present in true fungi. Galectin does not just occur in the cytoplasm, it is also present in the nucleus, on the cell surface, in the extracellular matrix, etc., and it is thought to be involved in many biological phenomena, including development, differentiation, morphogenesis, tumor metastasis, cell death, and RNA splicing.
Galectin-3 is a beta-galactoside-binding protein that has been named IgE-binding protein, CBP35, CBP30, Mac-2, L-29, L-31, L-34, etc., and structurally it is a chimera-type lectin composed of a sugar-chain-binding domain (galectin domain) and a non-lectin domain.
Its biological function is still uncertain, but many studies that should elucidate its function have been performed, and as a result participation of galectin-3 has been demonstrated in the biological phenomena of cell growth, adhesion, metastasis, and apoptosis. For example, a positive correlation has been shown between  galectin-3 expression and the degree of malignant transformation in certain types of cell lines. A positive correlation has also recently been shown between galectin-3 expression and degree of malignancy in certain types of malignant tumors, and measurement of galectin-3 is expected to possibly serve as an index of degree of tumor malignancy.
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